To help surgeons: biological adhesive developed in Moscow to stop heavy bleeding

To help surgeons: biological adhesive developed in Moscow to stop heavy bleeding
Photo: Photo by the Mayor and Moscow Government Press Service. Yevgeny Samarin
This medical product is made of a patient's blood plasma. It staunches bleeding, accelerates cell growth and promotes rapid tissue regeneration. With this adhesive applied, even deep wounds and severe burns heal faster.

A unique surgical adhesive to stop bleeding and heal wounds and burns has been developed in Moscow. It is effective even in cases where there is a threat to a patient's life. Clinical trials of the innovative product have been conducted at the Burdenko Neurosurgery Institute and Blokhin Cancer Research Centre. Medicine production has already been started.

The adhesive is prepared before surgical intervention using 200 ml of a patient's blood plasma taken two to three days before the surgery. This medical procedure lasts about an hour. The substance obtained is to be stored in the refrigerator, so before applying it needs to be warmed up to human body temperature. As a rule, 1 to 20 ml is needed for a surgery.

Surgeons put adhesive on the wound after treatment. It glues up the tissues, covering them like a film. The substance dissolves in two to eight weeks, so patients do not have to visit the doctor once again.

"The haemostasis process activated by this unique adhesive is similar to the natural coagulation. The medicine also accelerates cell growth and promotes damaged tissue restoration. As a result, deep wounds and severe burns heal faster," said Konstantin Bylov, Director General of the adhesive developer, a Zelenograd Innovation Cluster resident.

The innovative adhesive has foreign analogues, but they are made of plasma taken from other donors, while the one developed in Moscow is obtained directly from the blood plasma of the patient before the surgery.

Its costs about 50 percent less than its foreign analogues.

There are also other biological adhesives, mainly synthetic, available on the market, but they are intended only for external injuries treatment and may not be used for open surgeries.

"New biological adhesive will be of great help in complex surgical operations. More than 900 successful operations have already been performed in various Russian hospitals with the use of this product," Konstantin Bylov said.

35 Moscow technoparks have also been engaged in innovative solutions within three investment priority projects. Residents of these specialised territories have been developing and applying cutting-edge technology in a variety of areas, ranging from development of future urban transport to footwear manufacture.

Kalibr Technology Park develops advanced powerful drone engine Moscow technopark develops an innovative way to stop bleeding

So, for example, residents of Kalibr, one of the three investment priority projects, produce autonomous cars and buses. For this purpose, a 400m track with stops and pedestrian crossings was built. Kalibr has developed a new turbojet drone engine. The new product is expected to become one of the most advanced 50 kg thrust drone engines after all the tests are completed. In addition, an innovative haemostatic powder has been developed in Mosmedpark (based on Strogino Technopark). The medical device can stop even heavy, potentially fatal bleeding in just three minutes.

Moscow offers a comprehensive system of support for technoparks and their residents, including tax benefits on income, land and property, as well as a reduction in land rent rates. It reduces a tax burden on businesses and investors by about 25 percent compared to the ordinary level.

Technopark management companies can also receive soft loans (up to RUB 50 million) at 2 percent per annum for up to five years. Moreover, a loan repayment compensation for technopark development is provided. This is co-financing within the key rate (7.75 percent) up to RUB 300 million per year, including construction and installation works, updating, reconstruction and technical upgrade. Moscow technoparks are subordinated to the Moscow Department of Entrepreneurship and Innovative Development.

There is also Moscow Technopolis special economic zone (SEZ). It includes five sites with four of them located in Zelenograd and one in Pechatniki. The SEZ comprises a number of high-tech industries such as microelectronics, optics, robotics, medical technology and equipment. It also produces new composites. Some SEZ enterprises are engaged in the development of information, communication and energy-efficient technologies, including nanotechnology. There are even companies specialising in orthopaedic footwear manufacture.

In particular, one of the Moscow Technopolis residents has created a miniature automated syringe dispenser for drug administration. It is about six times lighter than its analogues. Doctors may carry a new device in their bags to quickly provide first aid. Another SEZ resident has developed a RFID tag to track luggage at airports and during flights. This will help to have less cases of lost luggage. An innovative water body monitoring system independently determines the type of an incident and sends the coordinates to rescuers. It has video cameras and detecting devices such as radars and thermal imagers. The system is activated if people step on thin ice, swim in wrong places or go into too cold water.

SEZ residents enjoy tax incentives such as zero tax rate on income, property, land and transport. Also, it is a customs-free zone. The funds that companies have saved on tax payments can be invested to develop production, purchase equipment, introduce innovation, and enter international markets. SEZ is subordinated to the Department of Investment and Industrial Policy.